14 DAYS AGO • 7 MIN READ

🥯 Why Gluten May NOT Be The Problem

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Dr Karan's Weekly Dose

A weekly newsletter to help you live a happier, healthier life!

I want to start with an apology.

There is a large group of people I simply did not think about and literally hundreds of them, quite rightly, have called me out on it. I owe them an apology and this is it: I’m sorry.

When developing LOAM, I simply didn’t think about the burden carried by people with a true wheat allergy or non-celiac wheat sensitivity. Taken together, that’s millions of people.

The original LOAM formulation IS gluten-free, but still contains wheat and as I built it primarily for myself, it never crossed my mind that I might be excluding millions of people who can’t tolerate wheat.

That’s why we’ve been working around the clock to create an additional completely wheat-free version of LOAM. It’s still a 5-in-1, all-plant fiber formulation that will feed the full spectrum of bacteria in your gut microbiome. It’s live now and you can find it here.

That said, wheat is an incredible slow-fermenting fiber and is an excellent fiber source for people with no issues or sensitivity to it. The original formulation of LOAM hasn't gone anywhere; we've just released a new option for anyone with wheat sensitivities. Enjoy!

What you'll learn in this newsletter:

1. 🥯 Why Gluten May NOT Be The Problem

2. 🪥4 Steps To Supercharge Your Oral Health

3.🕰️ Why It's Never Too Late

Gut health

🥯 Why Gluten May NOT Be The Problem


When people experience bloating, abdominal pain or changes in bowel habits after eating wheat-based foods, like bread or pasta, it’s natural to pin the blame on gluten.

However, we’re increasingly coming to realise not all wheat-related problems are caused by gluten.

When people who report gluten sensitivity participate in blinded studies (where they don’t know whether they’re being given gluten to eat or not), only around 16-30% of such individuals actually have symptoms triggered by gluten (PMID: 41138740)

As a consequence, scientists now recognise other components of wheat may also cause allergic reactions or sensitivities.

One of these is fructans. These are a type of fermentable carbohydrate that naturally occurs in wheat, as well as other foods, like rye and onions. Fructans are poorly absorbed in the small intestine and can be fermented by gut bacteria, leading to gas, bloating and abdominal discomfort in susceptible individuals.

Scientists are also studying amylase-trypsin inhibitors (ATIs), proteins found in wheat that may stimulate the immune system in some people. Although their exact role remains unclear, they are another reminder that wheat is a complex food containing much more than gluten alone.

This growing body of research has led some experts to favour the term non-coeliac wheat sensitivity rather than non-coeliac gluten sensitivity, reflecting the possibility that gluten may not always be the villain, rather some other compound in the wheat.

What does this mean in practice?

1️⃣ Don’t self-diagnose. Coeliac disease and wheat allergy should always be excluded before making major dietary changes.

2️⃣ There is no one-size-fits-all explanation. One person may be sensitive to gluten, another to fructans, while another may be sensitive to a combination of dietary and lifestyle factors.

This is why I’m so pleased to announce the new wheat-free version of LOAM.

You can still get a third of your minimum daily fiber target in one go, but now you no longer need to worry about whether LOAM will trigger any wheat-based symptoms.


GENERAL health

🪥4 Steps To Supercharge Your Oral Health

For something we all do twice a day (at least) it’s remarkable how many of us don’t do it right.

I’m talking about brushing your teeth, or oral care more generally.

It’s worth taking oral care seriously.

It’s not just about preventing cavities and gum disease. Poor oral health has been associated with cardiovascular disease, type 2 diabetes and adverse pregnancy outcomes among others.

So, here’s what you need to know.

Your mouth pH should be around 7: neutral.

However, eating tends to lower the pH to around 5.5 making it more acidic. Over time, a more acidic oral environment leads to cavities.

Fortunately, when you stop eating, your mouth naturally returns to normal pH levels. Using an alkaline mouthwash can aid this process.

So, remember: every morning, after breakfast, brush, floss and use alkaline mouthwash for optimal oral health.

Hold on. Actually, that’s the wrong way round.

Even though this is the order many of us follow in taking care of our teeth, experts actually recommend the following.

Before breakfast:

1️⃣ Use a non-alcoholic, alkaline mouthwash

2️⃣ Floss

3️⃣ Use a tongue scraper

4️⃣ Brush

Plaque builds up during the night, so using mouthwash and floss before brushing helps loosen those particles making them easier to remove once you do start brushing.

Using a tongue scraper ensures your tongue is clean which will help prevent bad breath and may even improve your taste.

If all you do right now is just brush twice per day, start flossing. If you already floss, try adding just one of the other steps to take your oral health to the next level.

P.S quick note: if you’re an expert in your field, be it scientist, doctor, lawyer or chef, and you’re interested in growing your brand, social media presence or business...I’d love to help you. If you’re interested, more here:


REFLECTIONS

🕰️ Why It's Never Too Late

Here’s why it’s never too late to reinvent yourself.

People often tell themselves, “it’s too late to do X”, when what they really mean is “I’ve already invested too much to change”:-

  • 6 years of medical school
  • 10 years of this relationship
  • My whole life living in this town

This is a classic example of the sunk cost fallacy.

Whatever time or money you’ve spent in the past is gone (a “sunk” cost), regardless of what you do in the future. You’ll never get it back, so it shouldn’t make any difference to the decisions you make now.

So ask yourself this question: would I choose this life if I didn’t already have it?

If the answer to that question isn’t an unqualified “yes”, take it as your sign to reinvent something about yourself.

It doesn’t have to be as drastic as any of the examples above. You could just reinvent yourself as a person who goes to the gym once per week.

Start by filling in the information gaps:- (“what do I actually need to do at the gym?”, “how do you upload a video to Youtube? etc) and then take the smallest possible action to move yourself closer to your goal.

Here’s a real-life example:

A 42-year old high school teacher decided he’d like to work as a content writer for Youtubers. He wrote a script for a 30-second short on a topic he already knew well. He sent it cold to a well-known Youtuber, offering him the script for free.

The Youtuber took him up on his offer and that was the start of this individual’s career as a content writer. Today, he’s a member of my team


👋 Who are you again? I’m Karan Rajan - a doctor and curious explorer of all things health and wellness. I'm the founder of LOAM Science, a microbiome company aiming to create the best fiber product in the world! I host the Dr Karan Explores Podcast, where I talk to experts in science and medicine to cut through the BS of modern health advice. If you'd like an easy way to dig through the archive, you can ask me any questions about the podcast and talk to my digital librarian here. I've also written two books "This Book May Save Your Life" and "This Is Vital Information". I'm the Chief of Science of Throne, a smart gut health tracking device.

If you feel strongly about some health things or just want to say hi? Hit reply... I’d love to hear it and hear from you! (yes I read every reply!!!)

🤩 WEEKLY HIGHLIGHTS

A Video About Old People

Centenarians are remarkable people. How does someone who drinks and smokes every day live to 120? In this video, I explain the statistical mistake many people make when trying to learn from centenarians and what we should all be doing instead to enjoy a long, healthy life.

video preview

◀️ Dietitian Explains How To Uncomplicate Health Eating

Shyla Cadogan is a registered dietitian, an endometriosis patient and advocate, and a scientific advisory board member for LOAM! And the practical advice starts 30 seconds into this podcast interview. You can check it out here..

video preview

🤖 My Digital Librarian

My digital twin is at your beck and call 24/7. He'll answer any question you have about any of my videos all the while being unfailingly polite and less patronising than ChatGPT. Last week's pod with weight loss expert Dr Andrew Jenkinson is a case in point. Ask my virtual twin anything about the episode, or just watch it here.

video preview

📝 WHAT I'M DOING THIS WEEK

🍽️ Try Out My NEW Cooking Course

There are always a million and one ideas and things I want to do running through my head (often based on requests from you guys 😀) and one of those is how to eat better, healthier, with more fiber, more plants and more TASTE! I’m putting together an easy starter course for how to cook for your gut health. If you’re interested, you can sign-up here.


☕ Trying To Find Some Different Coffees

I spoke about how I use coffee as a supplement rather than a stimulant in this video, but I remain open to the possibility there might be at least one type of coffee I actually like. That being the case, I’m trying out a few different coffees to see if I can find something I actually enjoy. Open to suggestions!

🌾 Trying Out A New Source of Fiber

You’ll have noticed I talk about fiber diversity as well as amount (both super-important). With that in mind, I’m adding a new fiber source to my routine: buckwheat. Tune in next week, where I’ll share my buckwheat porridge recipe that’s high protein AND high fiber.

P.S I'm trying to broaden my knowledge beyond health and science and learn more about tech, politics and general world news...I feel like I've been submerging myself in a wellness bubble these last few years! I love reading this newsletter that gives me fact-checked, bite-sized and unbiased news to keep my dinner party conversations interesting!

Disclaimer: This blog is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this blog or materials linked from this blog is at the user’s own risk. The content of this blog is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay seeking medical advice for any medical condition they may have and should consult their healthcare professionals for any such conditions.

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© 2026 Dr Karan's Weekly Dose

Dr Karan's Weekly Dose

A weekly newsletter to help you live a happier, healthier life!