8 DAYS AGO • 8 MIN READ

🫩 Waking Up at 3am? Try This

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Dr Karan's Weekly Dose

A weekly newsletter to help you live a happier, healthier life!

Last week, I promised you my favourite new high-fiber, high-protein breakfast: buckwheat porridge, so here it is:

Soak 50g of buckwheat in 250ml of water for at least 4 hours or overnight.

Drain the water then pulse the buckwheat with 250ml milk (any type is fine) a few times in a food processor.

Cook over a low heat for 5-10 minutes and that's it.

That's 7g protein and 3g of fiber straight away, but you can add berries to up the fiber, and yoghurt or peanut butter to boost the protein.

And naturally, I throw in a cheeky serving of LOAM to boost the fiber even more because front-loading your daily fiber is a cheat code from the Gods.

Finally, despite the name, Buckwheat is completely gluten free, so if you have any type of gluten sensitivity, you can still give this breakfast a go.

What you'll learn in this newsletter:

1. 🚀 What Happens At More Than 30g of Fiber?

2. 🫩 Waking Up at 3am? Try This

3. 🐢 Take It Slow

Gut health

🚀 What Happens At More Than 30g Of Fiber


Regular readers of this newsletter will know how important dietary fiber is and the fact that 95% of people don’t eat the minimum recommended amount of 30g per day.

But 30g is the minimum.

And I was reminded of why eating more than 30g per day is important by a study (PMID 42387949) I read this week.

7000+ adults reported their levels of dietary fiber intake, while the researchers measured the following biomarkers:-

  • C-reactive protein (CRP) - a measure of inflammation
  • total cholesterol (TC)
  • LDL cholesterol
  • HDL cholesterol
  • triglycerides

Here’s what they found:

  1. A consistent inverse relationship between fiber intake and C-reactive protein. The lowest levels of CRP were seen at the highest intake of fiber - around 55g daily
  2. Triglycerides fell at around 40g of daily fiber
  3. In men, LDL cholesterol and total cholesterol decreased significantly at levels of 70g of fiber each day

And here are some important reminders:

  1. These are associations between fiber and reduced inflammation/lipid profile but this does not mean fiber causes these effects.
  2. These findings are limited to a single point in time - longitudinal research is required to see dietary fiber intake is linked to positive health outcomes over the long-term

This is why I'm so bullish on eating much more than 30g of fiber per day: 30g seems to be far from optimal.

That said, eating 60g or 70g of fiber every day is no mean feat. On a good day, I get around 50g from food (challenging enough!), but when life gets in the way, that can easily drop.

That’s why I use LOAM to get an extra 10g beyond my 30g target without having to create a whole extra meal. It's 10g of fiber that dissolves into any liquid without changing its taste or texture. Stir it into your morning coffee and you'll be on your fiber A-game straight away!


GENERAL health

🫩 Waking Up At 3am? Try This

Waking up at 3am and wondering why you said that thing to that girl in 2010 is no fun.

Yet 46% of Americans and an astonishing 83% of Brits report waking up at least once per night in surveys.

Here are some of the main culprits and what you can do about them:

1️⃣ Cortisol Rising

Cortisol naturally starts rising between 2am and 4am to prepare the body to wake. However, if you just naturally have higher levels of cortisol or are going through a particularly stressful time, that temporary spike can push levels too high and leave you staring at the ceiling.

Simple breathing techniques (4 seconds in, 8 seconds out or any 2:1 ratio) increase vagal nerve activity which promotes a rest state in the body.

2️⃣ Low blood sugar

If you have a high-carb dinner, particularly if you're pre-diabetic or diabetic, you may experience a drop in blood sugar during the night. Your body’s response? Press the big red button marked PANIC! and release cortisol and adrenaline to raise glucose levels.

Choose protein and complex carbs for your final meal and stop eating 3-4 hours before bed.

3️⃣ Temperature

To go to sleep and stay asleep, your body’s temperature needs to drop. Having a room or bed that’s too warm can disrupt sleep and cause you to wake during light sleep phases.

If you’re feeling hot in bed, experiment with removing pyjamas and bedclothes, but no need for peer review or publication of the data.

Heat-controlled mattresses are a thing if you have the money to spend on something like that.

4️⃣ Sleep apnea and mouth breathing

80% of obstructive sleep apnea (OSA) cases go undiagnosed according to the American Academy of Sleep Medicine.

As the night progresses, periods of REM sleep get longer and more frequent and this is when OSA sufferers are more likely to experience disrupted breathing. This is another reason why you might be waking up at 3am.

To diagnose OSA you need a sleep study, which can be done at home if necessary. Talk to your doctor or sleep specialist. Beyond that, you may find sleeping on your side and avoiding alcohol before bed help.


REFLECTIONS

🐢 Take It Slow

In our recent podcast conversation, neuroscientist TJ Power talked about digital anhedonia - the inability to find joy in either real life, or digital experiences that we once enjoyed

The theory is, it all stems from constant overstimulation from endless scrolling, short-form content and never-ending notifications.

By now, we all know these activities overload our dopamine receptors, which is what makes them so addictive.

The key to fighting dopamine addiction and digital anhedonia is to choose slow dopamine activities that provide slow, steady sources of pleasure. And the good news is, you already know how to do all of these things:

1️⃣ Read long books. Actually, read any books. It’s not the length of the book that’s important so much as how long you can sustain reading it.

2️⃣ Take a walk without your headphones. This is a big one for me given how useful walking meetings are. That said, when I’ve tried it, I’ve been surprised by how much I’ve noticed - sounds, smells and sights.

3️⃣ Write a letter. When was the last time you wrote a letter to someone you care about? Try it. It’ll mean more to you and them than any text or email.

4️⃣ Watch movies, TV etc without your phone. When you stop and think about it, it’s absolute madness to try to look at two screens at once, yet we all do it.

5️⃣ Learn a difficult skill:- cross-stitch, piano, origami, it all counts. You’ll be exercising cognitive skills you might not have used since you left education.

Yes, yes, we all know we should be doing some of these things and I’m as guilty as anyone of not doing them. However, the key, as always, is to start small.

I’ll be doing at least one this week, at least once. Why not try doing the same?

PS a lot of people who follow me are surprised to learn I actually have a podcast! It's not a boring 3-hour, watching paint dry podcast talking about protocols, nor is it a clickbait fear-mongering health podcast either.

It's a 30-45 min chat with literal world experts cutting through the bullshit of modern health advice with tips that are actually easy to follow whether you're a dialled-in biohacker or a more-couch-than-5k chocolate lover.

You can check it out here.


👋 Who are you again? I’m Karan Rajan - a doctor and curious explorer of all things health and wellness. I'm the founder of LOAM Science, a microbiome company aiming to create the best fiber product in the world! I host the Dr Karan Explores Podcast, where I talk to experts in science and medicine to cut through the BS of modern health advice. If you'd like an easy way to dig through the archive, you can ask me any questions about the podcast and talk to my digital librarian here. I've also written two books "This Book May Save Your Life" and "This Is Vital Information". I'm the Chief of Science of Throne, a smart gut health tracking device.

If you feel strongly about some health things or just want to say hi? Hit reply... I’d love to hear it and hear from you! (yes I read every reply!!!)

🤩 WEEKLY HIGHLIGHTS

⚠️ I Investigated The AI Doctor Epidemic

Epidemic is NOT an exaggeration. Social media is flooded with AI-generated content and if that were as far as went, so be it. But I've personally been impersonated as have many other medical influencers and I wanted to find out what was behind it all. This video is the result.

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🧬 The Stem Cell Scandal That Put A Famous Doctor In Hospital

I'd like to think that title says it all. This is an astonishing story from Scott Carney (who you should definitely check out online) about dodgy stem cell clinics, why people fall for scams and why scammers seem to get away with it. Definitely worth a listen.

video preview

🗄 From The Vaults

If the article above convinced you that you need to eat more fiber, that's great. But quantity isn't even half the story. I answer 16 different questions about fiber that were put to me by my viewers in this video.

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📝 WHAT I'M DOING THIS WEEK

💻 Working On The Content Creator Course

I’ve had a wild number of people register interest in working with me hands on to learn how to create educational content online and figure out social media as a professional! I love teaching and seeing others enjoy success, so I am very excited for this. I'm currently building out the syllabus and the live training session, so if you want to work with me, there's more info here.


✈️ Travel Hell!

I've got a hectic travel schedule the next week (as you read this I'll be somewhere in the skies about to embark on a brutal week of travel for conferences and work. Focus will be on getting penty of movement, hydration, fiber. Next week I'll tell you where I went and how best to get your fiber from your next travel destination! (obvously I'm packing a week's worth of LOAM travel sticks to keep me regular too!)

👶 Out And About With The Little One

Now my little gremlin is almost 4 months old, we're exposing his immune system to more variety to give it some resilience. This means more outings to the supermarket, the post office, the local park…even an afternoon tea parlour the other day! Different environmental microbome, different smells, new sensory inputs…immune and developmental boosts for the win!

P.S I'm trying to broaden my knowledge beyond health and science and learn more about tech, politics and general world news...I feel like I've been submerging myself in a wellness bubble these last few years! I love reading this newsletter that gives me fact-checked, bite-sized and unbiased news to keep my dinner party conversations interesting!

Disclaimer: This blog is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this blog or materials linked from this blog is at the user’s own risk. The content of this blog is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay seeking medical advice for any medical condition they may have and should consult their healthcare professionals for any such conditions.

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© 2026 Dr Karan's Weekly Dose

Dr Karan's Weekly Dose

A weekly newsletter to help you live a happier, healthier life!